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Recombinant CD47 抗体 (AA 18-135)

This anti-CD47 antibody is a 兔 单克隆 antibody detecting CD47 in IHC, ELISA, IHC (f) 和 Coat. Suitable for 人.
产品编号 ABIN7127215
发货至: 中国

Quick Overview for Recombinant CD47 抗体 (AA 18-135) (ABIN7127215)

抗原

See all CD47 抗体
CD47

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This CD47 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Coating (Coat)
  • 抗原表位

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    AA 18-135

    特异性

    This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    A recombinant fragment (around aa 18-135) of human CD47 protein (exact sequence is proprietary)

    亚型

    IgG
  • 应用备注

    Known_Application: ELISA (For coating, order antibody without BSA), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human placenta, brain or ovarian tumors (IHC).

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    CD47

    别名

    CD47

    背景

    Antigenic Surface Determinant Protein OA3, IAP, Integrin Associated Protein, Integrin Associated Signal Transducer, MER6, OA3, Protein MER6, Rh Related Antigen,CD47 / IAP (Integrin Associated Protein)
    Cellular localisation: Cell Surface

    分子量

    ~50kDa

    基因ID

    961, 446414

    UniProt

    Q08722
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