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CREB5 抗体

CREB5 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7127208
发货至: 中国
  • 抗原 See all CREB5 抗体
    CREB5 (CAMP Responsive Element Binding Protein 5 (CREB5))
    适用
    • 26
    • 19
    • 5
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    • 3
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    • 2
    • 1
    宿主
    • 38
    • 4
    小鼠
    克隆类型
    • 40
    • 2
    单克隆
    标记
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This CREB5 antibody is un-conjugated
    应用范围
    • 42
    • 21
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    特异性
    The ATF/CREB family consists of a series of transcription factors that function by binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB-3 and Luman), CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. These transcription factors share terminal leucine zipper dimerization and basic DNA binding domains and are highly variable in their N-termini. Although each of the ATF/ CREB proteins bind CREs in their homodimeric form, they can also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. Protein kinase A- mediated CREB phosphorylation induces association with a nuclear protein designated CBP (CREB-binding protein), which may represent a CREB coactivator. CRE-BPa is a nuclear protein that binds DNA as a homodimer but can also form a heterodimer with ATF-2 or Jun.
    交叉反应 (详细)
    Human. Predicted to work with Mouse and Rat.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human CREB5 protein
    亚型
    IgG2b
    Top Product
    Discover our top product CREB5 Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa, U87 or K562 cells.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    CREB5 (CAMP Responsive Element Binding Protein 5 (CREB5))
    别名
    CREB5 (CREB5 产品)
    别名
    CREB5 antibody, CRE-BPA antibody, Crebpa antibody, D430026C09Rik antibody, RGD1566107 antibody, cAMP responsive element binding protein 5 antibody, CREB5 antibody, creb5 antibody, Creb5 antibody
    背景
    CAMP response element-binding protein CREBPa (CRE-BPa), cAMP responsive element binding protein 5 isoform alpha, CRE BPA, CREBPA, cyclic AMP responsive element binding protein 5,CREB5 / CRE-BPa
    Cellular localisation: Nucleus.
    分子量
    57kDa
    基因ID
    9586, 437075
    UniProt
    Q02930
    途径
    Thyroid Hormone Synthesis
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