CREB5 抗体
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- 抗原 See all CREB5 抗体
- CREB5 (CAMP Responsive Element Binding Protein 5 (CREB5))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CREB5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- 特异性
- The ATF/CREB family consists of a series of transcription factors that function by binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB-3 and Luman), CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. These transcription factors share terminal leucine zipper dimerization and basic DNA binding domains and are highly variable in their N-termini. Although each of the ATF/ CREB proteins bind CREs in their homodimeric form, they can also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. Protein kinase A- mediated CREB phosphorylation induces association with a nuclear protein designated CBP (CREB-binding protein), which may represent a CREB coactivator. CRE-BPa is a nuclear protein that binds DNA as a homodimer but can also form a heterodimer with ATF-2 or Jun.
- 交叉反应 (详细)
- Human. Predicted to work with Mouse and Rat.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human CREB5 protein
- 亚型
- IgG2b
- Top Product
- Discover our top product CREB5 Primary Antibody
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, U87 or K562 cells.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- CREB5 (CAMP Responsive Element Binding Protein 5 (CREB5))
- 别名
- CREB5 (CREB5 产品)
- 背景
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CAMP response element-binding protein CREBPa (CRE-BPa), cAMP responsive element binding protein 5 isoform alpha, CRE BPA, CREBPA, cyclic AMP responsive element binding protein 5,CREB5 / CRE-BPa
Cellular localisation: Nucleus. - 分子量
- 57kDa
- 基因ID
- 9586, 437075
- UniProt
- Q02930
- 途径
- Thyroid Hormone Synthesis
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