CREB5 抗体
Quick Overview for CREB5 抗体 (ABIN7127208)
抗原
See all CREB5 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The ATF/CREB family consists of a series of transcription factors that function by binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB-3 and Luman), CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. These transcription factors share terminal leucine zipper dimerization and basic DNA binding domains and are highly variable in their N-termini. Although each of the ATF/ CREB proteins bind CREs in their homodimeric form, they can also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. Protein kinase A- mediated CREB phosphorylation induces association with a nuclear protein designated CBP (CREB-binding protein), which may represent a CREB coactivator. CRE-BPa is a nuclear protein that binds DNA as a homodimer but can also form a heterodimer with ATF-2 or Jun.
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交叉反应 （详细）
- Human. Predicted to work with Mouse and Rat.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human CREB5 protein
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亚型
- IgG2b
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anti-CAMP Responsive Element Binding Protein 5 (CREB5) (AA 1-99) antibody
CREB5 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 8A5 unconjugated
anti-CAMP Responsive Element Binding Protein 5 (CREB5) (AA 1-99) antibodyCREB5 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-CAMP Responsive Element Binding Protein 5 (CREB5) (AA 1-508) antibodyCREB5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 5 (CREB5) (AA 1-508) antibodyCREB5 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 5 (CREB5) (AA 47-96) antibodyCREB5 适用: 人, 大鼠, 犬, 豚鼠, 马, 兔, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 5 (CREB5) (AA 151-200) antibodyCREB5 适用: 小鼠, 犬, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 5 (CREB5) (AA 210-330) antibodyCREB5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, U87 or K562 cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CREB5 (CAMP Responsive Element Binding Protein 5 (CREB5))
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别名
- CREB5
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背景
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CAMP response element-binding protein CREBPa (CRE-BPa), cAMP responsive element binding protein 5 isoform alpha, CRE BPA, CREBPA, cyclic AMP responsive element binding protein 5,CREB5 / CRE-BPa
Cellular localisation: Nucleus. -
分子量
- 57kDa
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基因ID
- 9586, 437075
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UniProt
- Q02930
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途径
- Thyroid Hormone Synthesis
抗原
-
