MED7 抗体
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- 抗原 See all MED7 抗体
- MED7 (Mediator Complex Subunit 7 (MED7))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MED7 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)
- 特异性
- MED7, also known as HKQ, QK, QK3 or quaking, is a 341 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one KH domain. Expressed in the frontal cortex of the brain, MED7 functions as an RNA-binding protein that plays an important role in myelinization and specifically binds to the RNA core sequence 5'-NACUAAY-N(1,20)-UAAY-3'. Additionally, MED7 regulates pre-mRNA splicing, and mRNA export and is involved in protecting and promoting the stability of select mRNAs. MED7 may be methylated by PRMT1 and may also be phosphorylated at its C-terminus, an event that decreases MED7 mRNA-binding affinity. Defects or deletions in the gene encoding MED7 are associated with astrocytic tumors and may be involved in the pathogenesis of schizophrenia. Multiple isoforms of MED7 exist due to alternative splicing events.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human MED7 protein
- 亚型
- IgG2b
- Top Product
- Discover our top product MED7 Primary Antibody
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anti-Mediator Complex Subunit 7 (MED7) (AA 1-233) antibody
MED7 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3E7 unconjugated
anti-Mediator Complex Subunit 7 (MED7) (AA 1-233) antibodyMED7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D7 unconjugated
anti-Mediator Complex Subunit 7 (MED7) (N-Term) antibodyMED7 适用: 人, 小鼠, 犬, 兔, Cow, 豚鼠, 马, 大鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 7 (MED7) (Middle Region) antibodyMED7 适用: 人, 小鼠, 犬, 兔, Cow, 豚鼠, 马, 大鼠, 斑马鱼 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 7 (MED7) (AA 1-233) antibodyMED7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 7 (MED7) antibodyMED7 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 7 (MED7) (AA 1-233) antibodyMED7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mediator Complex Subunit 7 (MED7) (N-Term) antibodyMED7 适用: 人, 小鼠, 犬, 兔, Cow, 豚鼠, 马, 大鼠, 斑马鱼, Pig, Bat, Hamster, 猴, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 7 (MED7) (AA 143-192) antibodyMED7 适用: 人, 小鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼, Pig, Bat, Hamster, 猴, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 7 (MED7) (N-Term) antibodyMED7 适用: 人, 小鼠, 犬, 兔, Cow, 豚鼠, 马, 大鼠, 斑马鱼, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: ELISA (use assay dependent concentration), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, U-251 MG or CACO-2 cells.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- MED7 (Mediator Complex Subunit 7 (MED7))
- 别名
- MED7 (MED7 产品)
- 背景
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Activator recruited cofactor 34 kDa component, ARC34, Cofactor required for Sp1 transcriptional activation, subunit 9, 33 kDa, CRSP complex subunit 9, CRSP9, hMED7, Mediator of RNA polymerase II transcription subunit 7, RNA polymerase transcriptional regulation mediator subunit 7 homolog, Transcriptional coactivator CRSP33,MED7
Cellular localisation: Nucleus. Nuclear bodies. - 分子量
- 27.2kDa
- 基因ID
- 9443, 279902
- UniProt
- O43513
- 途径
- Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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