ADIPOQ 抗体
Quick Overview for ADIPOQ 抗体 (ABIN7127173)
抗原
See all ADIPOQ 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore, adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism. Clone ADPN/4256 is used to detect plasma adiponectin concentrations. Clone ADPN/4256 is also used in a combination ELISA with clone ADPN/4255, acting as the capture antibody.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Synthetic peptide corresponding to the tail region of the Adiponectin molecule.
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亚型
- IgG1
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anti-Adiponectin (ADIPOQ) (AA 151-244) antibody
ADIPOQ 适用: 人, 小鼠, 大鼠, Cow, Pig WB, ELISA, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Adiponectin (ADIPOQ) (AA 111-244) antibodyADIPOQ 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adiponectin (ADIPOQ) (AA 18-244) antibodyADIPOQ 适用: 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adiponectin (ADIPOQ) (AA 19-244) antibodyADIPOQ 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adiponectin (ADIPOQ) (AA 111-244) antibodyADIPOQ 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Adiponectin (ADIPOQ) (AA 17-243) antibodyADIPOQ 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adiponectin (ADIPOQ) (AA 145-226) antibodyADIPOQ 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ADPN-1370 unconjugated
anti-Adiponectin (ADIPOQ) (AA 16-154) antibodyADIPOQ 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1E10D5 unconjugated
anti-Adiponectin (ADIPOQ) (AA 16-154) antibodyADIPOQ 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3A12D5 unconjugated
anti-Adiponectin (ADIPOQ) (AA 108-244) antibodyADIPOQ 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: ELISA (For coating, use antibody without BSA), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa cells. Human kidney.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- ADIPOQ (Adiponectin (ADIPOQ))
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别名
- ADIPOQ
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背景
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Adiponectin, Adipocyte complement-related 30 kDa protein (ACRP30), Adipocyte-specific secretory protein, Adiponectin, C1Q and collagen domain containing (ACDC), ADIPOQ, Adipose most abundant gene transcript 1 protein, Adipose specific collagen like factor, ADIPQTL1, ADPN, APM-1, Gelatin-binding protein 28 (GBP28),Adiponectin (Marker of Obesity)
Cellular localisation: Cytoplasmic & Cell Surface -
分子量
- 26-30kDa
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基因ID
- 9370, 80485
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UniProt
- Q15848
抗原
-
