ZMYM3 抗体
Quick Overview for ZMYM3 抗体 (ABIN7127138)
抗原
See all ZMYM3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
 - Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZMYM3 (zinc finger MYM-type protein 3), also known as ZNF261 (zinc finger protein 261), XFIM, DXS6673E or MYM, is a 1,370 amino acid nuclear protein that contains nine MYM-type zinc fingers. Expressed in a variety of tissues, including heart, muscle and brain, ZMYM3 is thought to function as part of a histone deacetylase-containing complex that contains other proteins, such as HDAC1 and HDAC2, and may play a role in gene silencing through the modification of chromatin structure. Defects in the gene encoding ZMYM3 that lead to chromosomal translocations may be a cause of X-linked mental retardation. Two isoforms of ZMYM3 exist due to alternative splicing events.
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交叉反应 (详细)
 - Human.
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纯化方法
 - 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
 - Recombinant full-length human ZMYM3 protein
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亚型
 - IgG2a
 
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or Raji cells. Ubiquitious nuclear expression.
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限制
 - 仅限研究用
 
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浓度
 - 1.0 mg/mL
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缓冲液
 - Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
 - Azide free
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储存条件
 - -20 °C,-80 °C
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储存方法
 - Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
 - 24 months
 
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- ZMYM3 (Zinc Finger Protein 261 (ZMYM3))
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别名
 - ZMYM3
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背景
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                        DXS6673E, KIAA0385, MYM, XFIM, ZFP261, Zinc finger MYM type 3, Zinc finger MYM type protein 3, Zinc finger MYM-type protein 3, Zinc finger protein 261, ZNF198L2, ZNF261,ZMYM3
Cellular localisation: Nucleus. - 
                                            
分子量
 - 152kDa
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基因ID
 - 9203, 522684
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UniProt
 - Q14202
 
抗原
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