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ZMYM3 抗体

This anti-ZMYM3 antibody is a 小鼠 单克隆 antibody detecting ZMYM3 in WB, IF, FACS 和 IHC (f). Suitable for 人.
产品编号 ABIN7127138
发货至: 中国

Quick Overview for ZMYM3 抗体 (ABIN7127138)

抗原

See all ZMYM3 抗体
ZMYM3 (Zinc Finger Protein 261 (ZMYM3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ZMYM3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 特异性

    Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZMYM3 (zinc finger MYM-type protein 3), also known as ZNF261 (zinc finger protein 261), XFIM, DXS6673E or MYM, is a 1,370 amino acid nuclear protein that contains nine MYM-type zinc fingers. Expressed in a variety of tissues, including heart, muscle and brain, ZMYM3 is thought to function as part of a histone deacetylase-containing complex that contains other proteins, such as HDAC1 and HDAC2, and may play a role in gene silencing through the modification of chromatin structure. Defects in the gene encoding ZMYM3 that lead to chromosomal translocations may be a cause of X-linked mental retardation. Two isoforms of ZMYM3 exist due to alternative splicing events.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant full-length human ZMYM3 protein

    亚型

    IgG2a
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or Raji cells. Ubiquitious nuclear expression.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    ZMYM3 (Zinc Finger Protein 261 (ZMYM3))

    别名

    ZMYM3

    背景

    DXS6673E, KIAA0385, MYM, XFIM, ZFP261, Zinc finger MYM type 3, Zinc finger MYM type protein 3, Zinc finger MYM-type protein 3, Zinc finger protein 261, ZNF198L2, ZNF261,ZMYM3
    Cellular localisation: Nucleus.

    分子量

    152kDa

    基因ID

    9203, 522684

    UniProt

    Q14202
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