Recombinant RCAS1 抗体
Quick Overview for Recombinant RCAS1 抗体 (ABIN7127131)
抗原
See all RCAS1 (EBAG9) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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特异性
- EBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human full-length EBAG9 protein
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亚型
- IgG
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anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (AA 1-213) antibody
EBAG9 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A10 unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (AA 31-213) antibodyEBAG9 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) antibodyEBAG9 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CPTC-EBAG9-2 unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) antibodyEBAG9 适用: 人 IHC, IF, StM 宿主: 小鼠 Monoclonal CPTC-EBAG9-1 unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (C-Term) antibodyEBAG9 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (C-Term) antibodyVerified EBAG9 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (C-Term) antibodyEBAG9 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, 小鸡, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (AA 28-213) antibodyEBAG9 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (C-Term) antibodyEBAG9 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (AA 88-117) antibodyEBAG9 适用: 人 WB 宿主: 兔 Polyclonal RB41813 unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7, Jurkat or 293 cell lysates. Human skeletal muscle tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))
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别名
- EBAG9
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背景
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BAG9, cancer associated surface antigen, cancer associated surface antigen RCAS1, EB9, estrogen receptor binding fragment associated gene 9, PDAF, receptor binding cancer antigen expressed on SiSo cells,RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9
Cellular localisation: Golgi apparatus. -
分子量
- 32kDa
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基因ID
- 9166, 409368
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UniProt
- O00559
抗原
-
