TSC22D1 抗体
Quick Overview for TSC22D1 抗体 (ABIN7127120)
抗原
See all TSC22D1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- Transforming growth factor i²-stimulated acts as a transcriptional regulator to modulate cell growth and differentiation and cell death. TSC-22 contains a leucine zipper domain as well as a nuclear export signal, resulting in cytoplasmic localization in living cells. However, concomitant with the induction of apoptosis, TSC-22 translocates from the cytoplasm to the nucleus and shows transcriptional regulatory activity. TSC-22 acts as a major downstream component in the TGFi² pathway and also the PPARi³ signaling pathway. The association of these two pathways with tumor suppression, and the significant downregulation of TSC-22 mRNA in various cancer types, such as brain and salivary gland tumors, imply an antiproliferative role for TSC-22.
-
交叉反应 (详细)
- Human.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant full-length human TSC22D1 protein
-
亚型
- IgG1
-
-
-
-
应用备注
-
Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or HepG2 cells.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- TSC22D1 (TSC22 Domain Family, Member 1 (TSC22D1))
-
别名
- TSC22D1
-
背景
-
Cerebral protein 2, Hucep2, KIAA1994, MGC17597, Regulatory protein TSC22, RP11 269C23.2, TGFB-stimulated clone 22 homolog, TGFB1I4, TGFbeta stimulated clone 22, Transcriptional regulator TSC 22, Transforming growth factor beta 1 induced transcript 4, Transforming growth factor beta 1 induced transcript 4 protein, TSC22D1,TSC22D1
Cellular localisation: Cytoplasm. Nucleus. Localized to nucleoplasm and nuclear bodies. -
分子量
- 16kDa
-
基因ID
- 8848, 436383
-
UniProt
- Q15714
抗原
-