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TSC22D1 抗体

This anti-TSC22D1 antibody is a 小鼠 单克隆 antibody detecting TSC22D1 in WB, IF 和 FACS. Suitable for 人.
产品编号 ABIN7127120
发货至: 中国

Quick Overview for TSC22D1 抗体 (ABIN7127120)

抗原

See all TSC22D1 抗体
TSC22D1 (TSC22 Domain Family, Member 1 (TSC22D1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TSC22D1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 特异性

    Transforming growth factor i²-stimulated acts as a transcriptional regulator to modulate cell growth and differentiation and cell death. TSC-22 contains a leucine zipper domain as well as a nuclear export signal, resulting in cytoplasmic localization in living cells. However, concomitant with the induction of apoptosis, TSC-22 translocates from the cytoplasm to the nucleus and shows transcriptional regulatory activity. TSC-22 acts as a major downstream component in the TGFi² pathway and also the PPARi³ signaling pathway. The association of these two pathways with tumor suppression, and the significant downregulation of TSC-22 mRNA in various cancer types, such as brain and salivary gland tumors, imply an antiproliferative role for TSC-22.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant full-length human TSC22D1 protein

    亚型

    IgG1
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or HepG2 cells.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    TSC22D1 (TSC22 Domain Family, Member 1 (TSC22D1))

    别名

    TSC22D1

    背景

    Cerebral protein 2, Hucep2, KIAA1994, MGC17597, Regulatory protein TSC22, RP11 269C23.2, TGFB-stimulated clone 22 homolog, TGFB1I4, TGFbeta stimulated clone 22, Transcriptional regulator TSC 22, Transforming growth factor beta 1 induced transcript 4, Transforming growth factor beta 1 induced transcript 4 protein, TSC22D1,TSC22D1
    Cellular localisation: Cytoplasm. Nucleus. Localized to nucleoplasm and nuclear bodies.

    分子量

    16kDa

    基因ID

    8848, 436383

    UniProt

    Q15714
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