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TRIM24 抗体

The 小鼠 单克隆 anti-TRIM24 antibody is suitable to detect TRIM24 in samples from 人. It has been validated for IF 和 FACS.
产品编号 ABIN7127116
发货至: 中国
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Quick Overview for TRIM24 抗体 (ABIN7127116)

抗原

See all TRIM24 抗体
TRIM24 (Tripartite Motif Containing 24 (TRIM24))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TRIM24 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS)
  • 特异性

    TIF1i±, also known as TRIM24, mediates transcriptional events by interactions with the AF2 region of several nuclear receptors, such as the estrogen, retinoic acid and vitamin D3 receptors. TIF1i± localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. TIF1i± is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains (RING, B-box type 1 and B-box type 2) and a coiled-coil region. The TIF1i± gene, which maps to human chromosome 7q33, encodes two alternatively spliced transcripts. However, the full length nature of one variant has not been determined. A TIF1i± homolog (designated bonus) has been identified in Drosophila and is associated with several genes that are implicated in the ecdysone pathway, a nuclear hormone receptor pathway required throughout Drosophila development, suggesting a conserved functional role for the protein throughout the course of evolution.

    交叉反应 (详细)

    Human

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant full-length human TRIM24 protein

    亚型

    IgG1
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or K562 cells.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    TRIM24 (Tripartite Motif Containing 24 (TRIM24))

    别名

    TRIM24

    背景

    E3 ubiquitin protein ligase TRIM24, hTIF1, PTC6, RING finger protein 82, RNF82, TF1A, TIF1 alpha, Transcriptional intermediary factor 1 alpha, Tripartite motif-containing protein 24,TRIM24 / TIF1 alpha
    Cellular localisation: Nucleus. Cytoplasm. Colocalizes with sites of active transcription.

    分子量

    117kDa

    基因ID

    8805, 490287

    UniProt

    O15164
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