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INSM2 抗体 (AA 432-540)

This anti-INSM2 antibody is a 小鼠 单克隆 antibody detecting INSM2 in IHC (f). Suitable for 人.
产品编号 ABIN7127097
发货至: 中国

Quick Overview for INSM2 抗体 (AA 432-540) (ABIN7127097)

抗原

See all INSM2 抗体
INSM2 (Insulinoma-Associated 2 (INSM2))

适用

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宿主

  • 20
小鼠

克隆类型

  • 20
单克隆

标记

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This INSM2 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 抗原表位

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    AA 432-540

    特异性

    IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription. INSM2 may function as a growth suppressor or tumor suppressor in liver cells and in certain neurons.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant fragment of human INSM2 protein (around aa 432-540) (exact sequence is proprietary)

    亚型

    IgG1
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human pancreas tissue.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    INSM2 (Insulinoma-Associated 2 (INSM2))

    别名

    INSM2

    背景

    IA1, Insulinoma associated protein 2 (IA2), Zinc finger protein IA6,Insulinoma Associated 2 / INSM2
    Cellular localisation: Nuclear

    分子量

    58kDa

    基因ID

    84684, 62813

    UniProt

    Q96T92
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