INSM2 抗体 (AA 432-540)
Quick Overview for INSM2 抗体 (AA 432-540) (ABIN7127097)
抗原
See all INSM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 432-540
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特异性
- IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription. INSM2 may function as a growth suppressor or tumor suppressor in liver cells and in certain neurons.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment of human INSM2 protein (around aa 432-540) (exact sequence is proprietary)
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亚型
- IgG1
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human pancreas tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- INSM2 (Insulinoma-Associated 2 (INSM2))
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别名
- INSM2
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背景
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IA1, Insulinoma associated protein 2 (IA2), Zinc finger protein IA6,Insulinoma Associated 2 / INSM2
Cellular localisation: Nuclear -
分子量
- 58kDa
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基因ID
- 84684, 62813
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UniProt
- Q96T92
抗原
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