GTF2IRD2 抗体
Quick Overview for GTF2IRD2 抗体 (ABIN7127095)
抗原
See all GTF2IRD2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The TFII-I family contains two highly homologous 949 amino acid proteins, GTF2IRD2 (GTF2I repeat domain containing 2) and GTF2IRD2B (general transcription factor II-I repeat domain-containing protein 2B). Localizing to the nucleus, these proteins are ubiquitously expressed and contain two GTF2I- like repeats. Encoded by a gene mapping to human chromosome 7q11.23, GTF2IRD2 and GTF2IRD2B are located in the Williams-Beuren syndrome (WBS) critical region. The deletion of genes located within this region results in WBS, possibly due to the unequal crossing over of highly homologous low-copy repeat sequences that flank the deleted region. WBS is an autosomal dominant genetic condition that is characterized by physical, cognitive and behavioral traits including facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human GTF2IRD2 protein
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亚型
- IgG2a
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anti-GTF2I Repeat Domain Containing 2 (GTF2IRD2) (AA 1-498) antibody
GTF2IRD2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-GTF2I Repeat Domain Containing 2 (GTF2IRD2) (AA 812-841), (C-Term) antibodyGTF2IRD2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB26073 unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or K562 cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))
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别名
- GTF2IRD2
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背景
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FP630, GTF2IRD2A, GTF2IRD2 alpha,GTF2IRD2
Cellular localisation: Nucleus. -
分子量
- 107kDa
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基因ID
- 84163, 647039
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UniProt
- Q86UP8
抗原
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