ZNF408 抗体
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北京 101111
Quick Overview for ZNF408 抗体 (ABIN7127076)
抗原
See all ZNF408 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the Kr ppel C2H2-type zinc-finger protein family, ZNF396 (zinc finger protein 396), also known as PRDM17 (PR domain zinc finger protein 17), is a 720 amino acid nuclear protein that contains ten C2H2-type zinc fingers. The gene encoding ZNF408 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human ZNF408 protein
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亚型
- IgG2b
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anti-Zinc Finger Protein 408 (ZNF408) (AA 471-720) antibody
ZNF408 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 408 (ZNF408) (AA 317-635) antibodyZNF408 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 408 (ZNF408) (AA 1-720) antibodyZNF408 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger Protein 408 (ZNF408) (AA 576-625) antibodyZNF408 适用: 人, Cow, 兔, 犬, 马, 猴, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 408 (ZNF408) (AA 648-697) antibodyZNF408 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 408 (ZNF408) (AA 396-445) antibodyZNF408 适用: 人, Cow, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 408 (ZNF408) (N-Term) antibodyZNF408 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), ,Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or Raji cells. Ubiquitious nuclear expression.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- ZNF408 (Zinc Finger Protein 408 (ZNF408))
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别名
- ZNF408
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背景
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EVR6, PFM14, PR domain zinc finger protein 17 (PRDM17), RP72, Zinc finger protein 408 (ZNF408),ZNF408 / PRDM17 (Transcription Factor)
Cellular localisation: Nucleus. -
分子量
- 118kDa
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基因ID
- 79797, 60300
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UniProt
- Q9H9D4
抗原
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