VCAM1 抗体
Quick Overview for VCAM1 抗体 (ABIN7127044)
抗原
See all VCAM1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- Recognizes a protein of 110 kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This MAb inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells.
-
交叉反应 (详细)
- Human.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant full-length human VCAM1 protein
-
亚型
- IgG1
-
-
-
-
应用备注
-
Known_Application: ELISA (For coating, order antibody without BSA),Optimal dilution for a specific application should be determined.
Positive_Control: Human placenta or tonsil
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
-
别名
- VCAM1
-
背景
-
CD106, INCAM-100, L1CAM, Vascular Cell Adhesion Molecule 1 (VCAM1), Vascular cell adhesion protein 1,CD106 / VCAM1 (Activated Endothelial Cell Marker)
Cellular localisation: Cell surface -
分子量
- 110kDa
-
基因ID
- 7412, 109225
-
UniProt
- P19320
-
途径
- Carbohydrate Homeostasis
抗原
-