TTR 抗体
Quick Overview for TTR 抗体 (ABIN7127029)
抗原
See all TTR 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermediate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein).
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human full-length protein
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亚型
- IgG2b
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anti-Transthyretin (TTR) (AA 1-147) antibody
TTR 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 2E10C5 unconjugated
anti-Transthyretin (TTR) (AA 20-147) antibodyTTR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transthyretin (TTR) (AA 21-147) antibodyTTR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transthyretin (TTR) (AA 21-150) antibodyTTR 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transthyretin (TTR) antibodyTTR 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Transthyretin (TTR) (AA 21-147) antibodyTTR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transthyretin (TTR) antibodyTTR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transthyretin (TTR) antibodyTTR 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 2A4 unconjugated
anti-Transthyretin (TTR) antibodyTTR 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal CPTC-TTR-1 unconjugated
anti-Transthyretin (TTR) (AA 21-147) antibodyTTR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D8 unconjugated
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应用备注
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Known_Application: Western Blot (2-4 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human liver.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- TTR (Transthyretin (TTR))
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别名
- TTR
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背景
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Transthyretin, PALB, HsT2651, prealbumin, amyloidosis type 1, ATTR, TBPA, CTS, CTS1, carpal tunnel syndrome 1, thyroxine-binding prealbumin, prealbumin, HEL111, TTR protein, Epididymis luminal protein 111, prealbumin thyroxine binding, senile systemic amyloidosis antibody,Transthyretin (Prealbumin)
Cellular localisation: Secreted. Cytoplasm. -
分子量
- 15kDa
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基因ID
- 7276, 427202
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UniProt
- P02766
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途径
- Hormone Transport
抗原
-
