MLX 抗体
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北京 101111
Quick Overview for MLX 抗体 (ABIN7126996)
抗原
See all MLX 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Max is a nuclear localized bHLH-Zip protein that forms homodimers or heterodimers with Myc family members, including Myc, Mad1, Mad3, Mad4, Mxi1 and Mnt (or Rox). These dimers bind to the E-box sequence CACGTG in order to regulate cell growth, proliferation and apoptosis. Mlx (Max-like protein X) is a bHLH-Zip protein that is structurally and functionally related to Max. Like Max, Mlx is broadly expressed in many tissues and has a long half-life. Mlx also forms homodimers or heterodimers with members of the Myc family, specifically Mad1, Mad4 and Rox, and members of the Mondo family, to repress or activate transcription from CACGTG E-boxes. MondoA forms weak homodimers and preferentially forms heterodimers with Mlx. The MondoA/Mlx complex is primarily localized to the cytoplasm, but will translocate to the nucleus in response to leptomycin B. Mlx can also dimerize with WBSCR14, a protein involved in Williams-Beuren syndrome (WBS), to repress E-box transcription, which provides further evidence that Mlx is a critical element in a transcription factor network.
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交叉反应 （详细）
- Human
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human MLX protein
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亚型
- IgG2b
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anti-MAX-Like Protein X (MLX) (Internal Region) antibody
MLX 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MAX-Like Protein X (MLX) (AA 125-151) antibodyMLX 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22641 unconjugated
anti-MAX-Like Protein X (MLX) (C-Term) antibodyMLX 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 山羊, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAX-Like Protein X (MLX) (C-Term) antibodyMLX 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 山羊, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAX-Like Protein X (MLX) (N-Term) antibodyMLX 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 山羊, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAX-Like Protein X (MLX) (AA 1-244) antibodyMLX 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MAX-Like Protein X (MLX) (AA 1-244) antibodyMLX 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1C3 unconjugated
anti-MAX-Like Protein X (MLX) (AA 201-250) antibodyMLX 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 山羊, 马, 兔, 斑马鱼, Hamster, 猴, Bat, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAX-Like Protein X (MLX) (Center) antibodyMLX 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-MAX-Like Protein X (MLX) (Internal Region) antibodyVerified MLX 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or MCF7 cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- MLX (MAX-Like Protein X (MLX))
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别名
- MLX
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背景
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BHLHd13, Class D basic helix-loop-helix protein 13, MAD7, Max-like bHLHZip protein, Max-like protein X, MLXIP, MONDOA, MXD7, Protein BigMax, Protein Mlx, Transcription factor-like protein 4 (TCFL4),MLX
Cellular localisation: Nucleus and cytoplasm. -
分子量
- 30kDa
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基因ID
- 6945
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UniProt
- Q9UH92
抗原
-
