TARBP2 抗体
Quick Overview for TARBP2 抗体 (ABIN7126994)
抗原
See all TARBP2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- TRBP2, also known as TARBP2 (trans-activation-responsive (HIV-1) RNA binding protein 2), TRBP1 or TRBP, is a nuclear protein that contains three DRBM (double-stranded RNA-binding) domains. TRBP binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. The third DRBM motif in the C-terminus of human TRBP2 can interact with and inhibit PKR activity, thereby increasing HIV-1 long terminal repeat (LTR) expression. In addition, TRBP2 functions as a component of a Dicer-containing complex and associates with the catalytic subunit of the RNA-induced silencing complex (RISC), namely eIF2C2. TRBP2 is essential for Dicer stability and the proper assembly of RISC. This suggests that TRBP2, in association with Dicer, plays an important role in the processing of miRNAs (microRNAs).
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human TARBP2 protein
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亚型
- IgG2a
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anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) antibody
TARBP2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 141-250) antibodyTARBP2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 141-250) antibodyTARBP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H1 unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 1-366) antibodyTARBP2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 1-366) antibodyTARBP2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 340-390) antibodyTARBP2 适用: 人, 小鼠, 大鼠, 马, 猴, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 1-366) antibodyTARBP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 60-89), (N-Term) antibodyTARBP2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33928 unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 1-366) antibodyTARBP2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 1-366) antibodyTARBP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7 or HeLa cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))
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别名
- TARBP2
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背景
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LOQS, Prbp, RISC loading complex subunit TARBP2, TAR (HIV 1) RNA binding protein 2, TAR RNA Binding Protein 2, TARBP2 RISC loading complex RNA binding subunit, Trans-activation-responsive RNA-binding protein, TRBP, TRBP1,TRBP2 / TARBP2
Cellular localisation: Cytoplasm. Cytoplasm > perinuclear region. Nucleus. -
分子量
- 45kDa
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基因ID
- 6895, 326
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UniProt
- Q15633
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途径
- Regulatory RNA Pathways, Ribonucleoprotein Complex Subunit Organization
抗原
-
