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SOX9 抗体 (AA 393-508)

This anti-SOX9 antibody is a 小鼠 单克隆 antibody detecting SOX9 in IHC (f). Suitable for 人.
产品编号 ABIN7126960
发货至: 中国

Quick Overview for SOX9 抗体 (AA 393-508) (ABIN7126960)

抗原

See all SOX9 抗体
SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SOX9 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 抗原表位

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    AA 393-508

    特异性

    The specificity of this monoclonal antibody to its intended target was validated by HuProtTMArray, containing more than 19,000, full-length human proteins.Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant humanSOX9 protein fragment (aa 393-508) (exact sequence is proprietary)

    亚型

    IgG2b
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: HepG2 cells. Human pancreas

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

    别名

    SOX9

    背景

    Campomelic Dysplasia Autosomal Sex Reversal (CMD1), SRA1, SRXX2, SRY (sex determining region Y) box 9, SRY related HMG box gene 9, Transcription factor SOX9,SOX9 / SRY-box 9
    Cellular localisation: Nuclear

    分子量

    65kDa

    基因ID

    6662, 647409

    UniProt

    P48436

    途径

    EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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