IL-25 抗体
Quick Overview for IL-25 抗体 (ABIN7126941)
抗原
See all IL-25 (IL25) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. Interleukin-17 (IL-17) and its cognate receptor, IL-17R, are an example of such a cytokine receptor pair. Originally identified as a rodent cDNA termed CTLA8, IL-17 is capable of inducing the secretion of IL-6 and IL-8 and augmenting the expression of ICAM-1 in human fibroblast cultures. The IL-17 protein exhibits a striking degree of homology with the HSV-13 protein which mimics its function. The IL-17 receptor is a type I transmembrane protein 864 amino acids in length that is highly expressed in spleen and kidney.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment of human IL25 protein (exact sequence is proprietary)
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亚型
- IgG1
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human brain, kidney or lung.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- IL-25 (IL25) (Interleukin 25 (IL25))
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别名
- IL25
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背景
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IL-17E, IL-25, IL17e, IL25, Interleukin 17E, Interleukin 25, Interleukin-17E,Interleukin-25 (IL-25) / IL-17E
Cellular localisation: Secreted. -
分子量
- 20kDa
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基因ID
- 64806, 302036
抗原
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