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IL-25 抗体

This 小鼠 单克隆 antibody specifically detects IL-25 in IHC (f). It exhibits reactivity toward 人.
产品编号 ABIN7126941
发货至: 中国
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Quick Overview for IL-25 抗体 (ABIN7126941)

抗原

See all IL-25 (IL25) 抗体
IL-25 (IL25) (Interleukin 25 (IL25))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-25 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 特异性

    Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. Interleukin-17 (IL-17) and its cognate receptor, IL-17R, are an example of such a cytokine receptor pair. Originally identified as a rodent cDNA termed CTLA8, IL-17 is capable of inducing the secretion of IL-6 and IL-8 and augmenting the expression of ICAM-1 in human fibroblast cultures. The IL-17 protein exhibits a striking degree of homology with the HSV-13 protein which mimics its function. The IL-17 receptor is a type I transmembrane protein 864 amino acids in length that is highly expressed in spleen and kidney.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant fragment of human IL25 protein (exact sequence is proprietary)

    亚型

    IgG1
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human brain, kidney or lung.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    IL-25 (IL25) (Interleukin 25 (IL25))

    别名

    IL25

    背景

    IL-17E, IL-25, IL17e, IL25, Interleukin 17E, Interleukin 25, Interleukin-17E,Interleukin-25 (IL-25) / IL-17E
    Cellular localisation: Secreted.

    分子量

    20kDa

    基因ID

    64806, 302036
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