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Recombinant PARVG 抗体

This anti-PARVG antibody (ABIN7126931) is a Rabbit Monoclonal antibody detecting PARVG in IHC (f). Suitable for Human.
产品编号 ABIN7126931
发货至: 中国

Quick Overview for Recombinant PARVG 抗体 (ABIN7126931)

抗原

See all PARVG 抗体
PARVG (Parvin, gamma (PARVG))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This PARVG antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 特异性

    The parvin family, including i±-parvin, i²-parvin and i³-parvin, link integrins and associated proteins with intracellular pathways, which regulate actin cytoskeletal dynamics and cell survival. All three family members localize to focal adhesions and function in cell adhesion, spreading, motility and survival through interactions with partners, such as integrin-linked kinase (ILK), paxillin, i±-actinin and testicular kinase 1. i±-parvin is widely expressed, with highest levels detected in the skeletal muscle, heart, liver and kidney. A complex made up of i±-parvin, ILK and the LIM protein PINCH-1 is critical for cell survival in a variety of cells, including certain cancer cells, kidney podocytes and cardiac myocytes. i²-parvin links initial integrin signals to rapid actin reorganization, thereby playing a critical role in fibroblast migration. The ILK-i³-parvin complex is essential for the establishment of cell polarity required for leukocyte migration.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    GST-tagged recombinant protein corresponding to human Gamma-parvin

    亚型

    IgG
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Jurkat cell lysate.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    PARVG (Parvin, gamma (PARVG))

    别名

    PARVG

    背景

    Gamma parvin, PARVG,Gamma-parvin (PARVG)
    Cellular localisation: Cytoplasm. Cell Surface.

    分子量

    37kDa

    基因ID

    64098

    UniProt

    Q9HBI0
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