PARVG 抗体
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北京 101111
Quick Overview for PARVG 抗体 (ABIN7126930)
抗原
See all PARVG 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The parvin family, including α-parvin, β-parvin and γ-parvin, link integrins and associated proteins with intracellular pathways, which regulate actin cytoskeletal dynamics and cell survival. All three family members localize to focal adhesions and function in cell adhesion, spreading, motility and survival through interactions with partners, such as integrin-linked kinase (ILK), paxillin, α-actinin and testicular kinase 1. α-parvin is widely expressed, with highest levels detected in the skeletal muscle, heart, liver and kidney. A complex made up of α-parvin, ILK and the LIM protein PINCH-1 is critical for cell survival in a variety of cells, including certain cancer cells, kidney podocytes and cardiac myocytes. β-parvin links initial integrin signals to rapid actin reorganization, thereby playing a critical role in fibroblast migration. The ILK-γ-parvin complex is essential for the establishment of cell polarity required for leukocyte migration.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- GST-tagged recombinant protein corresponding to human Gamma-parvin
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亚型
- IgG1
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anti-Parvin, gamma (PARVG) (AA 1-331) antibody
PARVG 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4E1 unconjugated
anti-Parvin, gamma (PARVG) (AA 1-331) antibodyPARVG 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Parvin, gamma (PARVG) (AA 1-331) antibodyPARVG 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Parvin, gamma (PARVG) (AA 1-331) antibodyPARVG 适用: 人 WB, IP 宿主: 小鼠 Polyclonal unconjugated
anti-Parvin, gamma (PARVG) (N-Term) antibodyPARVG 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: Jurkat cell lysate.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- PARVG (Parvin, gamma (PARVG))
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别名
- PARVG
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背景
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Gamma parvin, PARVG,Gamma-parvin
Cellular localisation: Cytoplasm. Cell Surface. -
分子量
- 37kDa
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基因ID
- 64098
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UniProt
- Q9HBI0
抗原
-
