Recombinant SELPLG 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant SELPLG 抗体 (ABIN7126929)
抗原
See all SELPLG 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Recombinant CD162 (Selectin P Ligand) Antibody
-
特异性
- CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
-
交叉反应 (详细)
- Human.
-
纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
免疫原
- Recombinant full-length human SELPLG (CD162) protein
-
亚型
- IgG1, kappa
-
-
-
-
应用备注
-
Known_Application: ELISA (For coating, order antibody without BSA),Optimal dilution for a specific application should be determined.
Positive_Control: Jurkat cells. Tonsil or Spleen.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
有效期
- 24 months
-
-
- SELPLG (Selectin P Ligand (SELPLG))
-
别名
- SELPLG
-
背景
-
CD162, CLA, Cutaneous lymphocyte associated antigen, P-selectin glycoprotein ligand 1, PSGL1, Selectin P ligand, SELPLG
Jurkat cells. Tonsil or Spleen.
-
分子量
- 43-120kDa
-
基因ID
- 6404, 591014
-
UniProt
- Q14242
抗原
-