Syndecan 1 抗体 (AA 90-250)
Quick Overview for Syndecan 1 抗体 (AA 90-250) (ABIN7126924)
抗原
See all Syndecan 1 (SDC1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 90-250
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特异性
- CD138, also designated syndecan-1, is a member of the syndecan family of four transmembrane spanning proteins capable of binding to heparan sulfate and chondroitin sulfate molecules. The syndecans main functions are to control cell growth and differentiation as well as to maintain cell adhesion and cell migration. Under normal conditions CD138 is predominantly expressed on mature plasma cells and early preB-cells, while other haematolymphoid cells are negative. Various types of epithelial cells are also CD138 positive. Squamous epithelial cells show strong membranous and some cytoplasmic staining, except for the mature superficial squamous epithelial cells which are unstained. Mature mesenchymal and neural tissues are not stained. Among haematolymphoid neoplasms, CD138 is expressed in practically all cases of plasma cell malignancies. Among non-haematolymphoid neoplasms the expression of CD138 is found in various types of carcinoma.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (around aa90-250) of human CD138 protein (exact sequence is proprietary)
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亚型
- IgG1
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anti-Syndecan 1 (SDC1) (AA 28-171) antibody
SDC1 适用: 人, 小鼠 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1A3H4 unconjugated
anti-Syndecan 1 (SDC1) (AA 210-238), (C-Term) antibodySDC1 适用: 人 WB, FACS, IF 宿主: 小鼠 Monoclonal 587CT7-3-6-5 unconjugated
anti-Syndecan 1 (SDC1) (AA 23-253) antibodySDC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syndecan 1 (SDC1) (AA 58-313) antibodySDC1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Syndecan 1 (SDC1) (AA 201-310) antibodySDC1 适用: 人, 大鼠, 小鼠, Cow WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Syndecan 1 (SDC1) (AA 25-240) antibodySDC1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Syndecan 1 (SDC1) (AA 23-254) antibodySDC1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Syndecan 1 (SDC1) (C-Term) antibodySDC1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Syndecan 1 (SDC1) (AA 23-254) antibodySDC1 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM45 unconjugated Recombinant Antibody
anti-Syndecan 1 (SDC1) (AA 25-240) antibodySDC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human tonsil or lymph node.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Syndecan 1 (SDC1)
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别名
- SDC1
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背景
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Heparan Sulfate Proteoglycan Fibroblast Growth Factor Receptor, SDC1, SYND1, Syndecan Proteoglycan 1, Syndecan-1,CD138 / Syndecan-1 (SDC1) (Plasma Cell Marker)
Cellular localisation: Cell Surface -
分子量
- 85kDa
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基因ID
- 6382, 224607
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UniProt
- P18827
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途径
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism
抗原
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