Recombinant S100P 抗体 (C-Term)
Quick Overview for Recombinant S100P 抗体 (C-Term) (ABIN7126919)
抗原
See all S100P 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D.S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment corresponding to C-terminal of human S100P protein
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亚型
- IgG
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human pancreatic adenocarcinoma, placenta or spleen tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- S100P (S100 Calcium Binding Protein P (S100P))
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别名
- S100P
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背景
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Migration inducing gene 9 (MIG9), S100E, S100 calcium binding protein P,S100P
Cellular localisation: Nucleus. Cytoplasm. Colocalizes with S100PBP in the nucleus. -
分子量
- 10kDa
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基因ID
- 6286, 2962
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UniProt
- P25815
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途径
- Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins
抗原
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