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Retinoid X Receptor gamma 抗体

The 小鼠 单克隆 anti-Retinoid X Receptor gamma antibody (ABIN7126909) specifically detects Retinoid X Receptor gamma in ELISA, IF, IP, Coat 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7126909
发货至: 中国
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Quick Overview for Retinoid X Receptor gamma 抗体 (ABIN7126909)

抗原

See all Retinoid X Receptor gamma (RXRG) 抗体
Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Retinoid X Receptor gamma antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Coating (Coat), Flow Cytometry (FACS)
  • 特异性

    Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARa, RARb and RARg, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRi±, RXRi² and RXRi³, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.

    交叉反应 (详细)

    Human. Predicted to react in Mouse, Rat and Chick.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant full-length human RXRG protein

    亚型

    IgG1
  • 应用备注

    Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: SK-MEL-30, U-2 OS or HeLa cells.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

    别名

    RXRG

    背景

    Nuclear receptor subfamily 2 group B member 3 (NR2B3), Retinoic X receptor gamma (RXRG), Retinoic acid receptor RXR gamma, RXR gamma, RXRC,RXRG / NR2B3 (Transcription Factor)
    Cellular localisation: Nucleus > Nucleoplasm > Nuclear bodies.

    分子量

    50.87kDa

    基因ID

    6258, 26550

    UniProt

    P48443

    途径

    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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