Retinoid X Receptor gamma 抗体
Quick Overview for Retinoid X Receptor gamma 抗体 (ABIN7126908)
抗原
See all Retinoid X Receptor gamma (RXRG) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARa, RARb and RARg, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRi±, RXRi² and RXRi³, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.
-
交叉反应 (详细)
- Human. Predicted to react in Mouse, Rat and Chick.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant full-length human RXRG protein
-
亚型
- IgG2b
-
-
-
-
应用备注
-
Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), ,Optimal dilution for a specific application should be determined.
Positive_Control: SK-MEL-30, U-2 OS or HeLa cells.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))
-
别名
- RXRG
-
背景
-
Nuclear receptor subfamily 2 group B member 3 (NR2B3), Retinoic X receptor gamma (RXRG), Retinoic acid receptor RXR gamma, RXR gamma, RXRC,RXRG / NR2B3 (Transcription Factor)
Cellular localisation: Nucleus > Nucleoplasm > Nuclear bodies. -
分子量
- 50.87kDa
-
基因ID
- 6258, 26550
-
UniProt
- P48443
-
途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
-