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Retinoid X Receptor beta 抗体

This 小鼠 单克隆 antibody specifically detects Retinoid X Receptor beta in WB, FACS, IF 和 IHC (f). It exhibits reactivity toward 人.
产品编号 ABIN7126907
发货至: 中国
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Quick Overview for Retinoid X Receptor beta 抗体 (ABIN7126907)

抗原

See all Retinoid X Receptor beta (RXRB) 抗体
Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Retinoid X Receptor beta antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 特异性

    Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARi±, RARi² and RARi³, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRi±, RXRi² and RXRi³, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant full-length human RXRB protein

    亚型

    IgG2a
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or HepG2 cells.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

    别名

    RXRB

    背景

    DAUDI6, H2RIIBP, MGC1831, MHC class I promoter binding protein, NR2B2, nuclear receptor subfamily 2 group B member 2, RCoR1, Retinoic acid receptor RXR beta, RXR beta,RXRB
    Cellular localisation: Nucleus.

    分子量

    50-54kDa

    基因ID

    6257, 388034

    UniProt

    P28702

    途径

    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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