Retinoid X Receptor beta 抗体
Quick Overview for Retinoid X Receptor beta 抗体 (ABIN7126907)
抗原
See all Retinoid X Receptor beta (RXRB) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARi±, RARi² and RARi³, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRi±, RXRi² and RXRi³, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human RXRB protein
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亚型
- IgG2a
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anti-Retinoid X Receptor, beta (RXRB) (Hinge Region) antibody
RXRB 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Retinoid X Receptor, beta (RXRB) (AA 74-123) antibodyRXRB 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, Pig, 猴, Bat WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoid X Receptor, beta (RXRB) (AA 70-83) antibodyVerified RXRB 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Retinoid X Receptor, beta (RXRB) (AA 161-260) antibodyRXRB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E6 unconjugated
anti-Retinoid X Receptor, beta (RXRB) (AA 161-260) antibodyRXRB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C8 unconjugated
anti-Retinoid X Receptor, beta (RXRB) (N-Term) antibodyRXRB 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoid X Receptor, beta (RXRB) antibodyRXRB 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Retinoid X Receptor, beta (RXRB) (AA 451-500) antibodyRXRB 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 马, 兔, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoid X Receptor, beta (RXRB) (AA 151-200) antibodyRXRB 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 马, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoid X Receptor, beta (RXRB) (AA 28-77) antibodyRXRB 适用: 人, 小鼠, 大鼠, 豚鼠, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or HepG2 cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))
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别名
- RXRB
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背景
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DAUDI6, H2RIIBP, MGC1831, MHC class I promoter binding protein, NR2B2, nuclear receptor subfamily 2 group B member 2, RCoR1, Retinoic acid receptor RXR beta, RXR beta,RXRB
Cellular localisation: Nucleus. -
分子量
- 50-54kDa
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基因ID
- 6257, 388034
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UniProt
- P28702
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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