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Retinoid X Receptor beta 抗体

RXRB 适用: 人 WB, FACS, IF, IHC (f) 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7126907
发货至: 中国
  • 抗原 See all Retinoid X Receptor beta (RXRB) 抗体
    Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))
    适用
    • 43
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    宿主
    • 38
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    小鼠
    克隆类型
    • 39
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    单克隆
    标记
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    This Retinoid X Receptor beta antibody is un-conjugated
    应用范围
    • 45
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    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARi±, RARi² and RARi³, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRi±, RXRi² and RXRi³, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human RXRB protein
    亚型
    IgG2a
    Top Product
    Discover our top product RXRB Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or HepG2 cells.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))
    别名
    RXRB (RXRB 产品)
    背景
    DAUDI6, H2RIIBP, MGC1831, MHC class I promoter binding protein, NR2B2, nuclear receptor subfamily 2 group B member 2, RCoR1, Retinoic acid receptor RXR beta, RXR beta,RXRB
    Cellular localisation: Nucleus.
    分子量
    50-54kDa
    基因ID
    6257, 388034
    UniProt
    P28702
    途径
    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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