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BCL6 抗体

This 小鼠 单克隆 antibody specifically detects BCL6 in FACS 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN7126901
发货至: 中国
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Quick Overview for BCL6 抗体 (ABIN7126901)

抗原

See all BCL6 抗体
BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This BCL6 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)
  • 特异性

    Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( L&H ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.

    交叉反应 (详细)

    Human. Predicted to react in mouse and rat.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant human BCL6 protein

    亚型

    IgG2b
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells),Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or MCF-7 cells.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

    别名

    BCL6

    背景

    B-cell lymphoma 5 protein (BCL5), B-Cell Lymphoma 6 Protein, BCL6A, cys his2 zinc finger transcription factor, Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3), Zinc finger and BTB domain-containing protein 27 (ZBTB27), Zinc Finger Protein 51 (ZNF51), zinc finger transcription factor BCL6S,BCL6
    Cellular localisation: Nucleus. Mitochondria.

    分子量

    95kDa

    基因ID

    604, 478588

    UniProt

    P41182

    途径

    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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