BCL2L2 抗体
Quick Overview for BCL2L2 抗体 (ABIN7126898)
抗原
See all BCL2L2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human full-length BCL2L2 protein
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亚型
- IgG2b
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应用备注
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Known_Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: PC-3, HEK293, HePG2, MCF-7 or U87 cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- BCL2L2 (BCL2-Like 2 (BCL2L2))
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别名
- BCL2L2
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背景
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BCL-W, BCL2-L-2, BCLW, KIAA0271, PPP1R51,BCL2-like 2 (BCL2L2) / BCL-W
Cellular localisation: Cytoplasm. Mitochondrion membrane. -
分子量
- 22-30kDa
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基因ID
- 599, 410026
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UniProt
- Q92843
抗原
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