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TRIM27 抗体

This anti-TRIM27 antibody is a 小鼠 单克隆 antibody detecting TRIM27 in IF 和 FACS. Suitable for 人.
产品编号 ABIN7126897
发货至: 中国

Quick Overview for TRIM27 抗体 (ABIN7126897)

抗原

See all TRIM27 抗体
TRIM27 (Tripartite Motif Containing 27 (TRIM27))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TRIM27 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS)
  • 特异性

    Defects in TRIM27 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving TRIM27/RFP is found in thyroid papillary carcinomas. Translocation t(6,10)(p21.3,q11.2) with RET. The translocation generates TRIM27/RET and delta TRIM27/RET oncogenes.

    交叉反应 (详细)

    Human. Predicted to react with Mouse and Rat.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant full-length human TRIM27 protein

    亚型

    IgG2a
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa, U87 or Raji cells.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    TRIM27 (Tripartite Motif Containing 27 (TRIM27))

    别名

    TRIM27

    背景

    AW538890, DAAP-182E11.3, MGC189472, Ret finger protein, RFP transforming protein, Rfp1, RING finger protein 76, RNF76, Tripartite motif-containing protein 27, Zinc finger protein RFP,TRIM27
    Cellular localisation: Nucleus. Cytoplasm. Nucleus > PML body. Nuclear or cytoplasmic depending on the cell type (By similarity). Colocalized with PML and EIF3S6 in nuclear bodies.

    分子量

    58.49kDa

    基因ID

    5987, 440382

    UniProt

    P14373
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