RBP4 抗体 (AA 29-148)
Quick Overview for RBP4 抗体 (AA 29-148) (ABIN7126875)
抗原
See all RBP4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 29-148
-
特异性
- Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal Vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP, resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with Insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.
-
交叉反应 （详细）
- Human
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant fragment (around aa29-148) of human RBP4 protein (exact sequence is proprietary)
-
亚型
- IgG2b
-
-
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 63-245) antibody
RBP4 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) antibodyRBP4 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) antibodyRBP4 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) antibodyRBP4 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 4C2 unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) antibodyRBP4 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal A2 unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) antibodyRBP4 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibodyRBP4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibodyRBP4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 18-201) antibodyRBP4 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C9 unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibodyRBP4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E3 unconjugated
-
-
应用备注
-
Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeP-G2 cells. Human kidney, pancreas or liver tissues.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- RBP4 (Retinol Binding Protein 4, Plasma (RBP4))
-
别名
- RBP4
-
背景
-
Plasma retinol binding protein 4 (PRBP), RDCCAS, Retinol binding protein 4 interstitial,RBP4 / Retinol Binding Protein 4
Cellular localisation: Secreted -
分子量
- 25kDa
-
基因ID
- 5950, 50223
-
UniProt
- P02753
-
途径
- Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
抗原
-
