OVOL2 抗体
Quick Overview for OVOL2 抗体 (ABIN7126865)
抗原
See all OVOL2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The ATF/CREB family consists of a series of transcription factors that function by binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB-3 and Luman), CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. These transcription factors share terminal leucine zipper dimerization and basic DNA binding domains and are highly variable in their N-termini. Although each of the ATF/ CREB proteins bind CREs in their homodimeric form, they can also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. Protein kinase A- mediated CREB phosphorylation induces association with a nuclear protein designated CBP (CREB-binding protein), which may represent a CREB coactivator. CRE-BPa is a nuclear protein that binds DNA as a homodimer but can also form a heterodimer with ATF-2 or Jun.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human OVOL2 protein
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亚型
- IgG1
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, U87 or K562 cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- OVOL2 (Ovo-Like 2 (OVOL2))
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别名
- OVOL2
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背景
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BA504H3.3, hOvo2, Ovo like 2, ovo-like zinc finger 2 (OVOL2), Transcription factor Ovo-like 2, Zinc finger protein 339 (ZNF339),OVOL2 / CRE-BPa
Cellular localisation: Nucleus. -
分子量
- 69.1kDa
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基因ID
- 58495, 437075
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UniProt
- Q9BRP0
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途径
- Tube Formation
抗原
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