SLAMF7 抗体 (AA 249-335)
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- 抗原 See all SLAMF7 抗体
- SLAMF7 (SLAM Family Member 7 (SLAMF7))
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抗原表位
- AA 249-335
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SLAMF7 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- CS1, also known as novel Ly9, SLAMF7, 19A24 or CRACC, is a homophilic cell surface receptor. It is a member of the SLAM (signaling lymphocytic activation molecule) family of receptors expressed on natural killer (NK) cells, T cells and stimulated B cells. CS1 contains immunoreceptor tyrosine-based switch motifs in its cytoplasmic domain but, unlike other SLAM receptors, it does not recruit SAP (SLAM-associated protein). In humans, CS1 activates NK cells through an EAT-2-mediated pathway that is SAP-independent. CS1 recruits and associates with EAT-2, a protein closely related to SAP. EAT-2 induces phosphorylation of CS1 which then, upon ligand binding, activates downstream cytotoxicity effectors PLC and PI 3K. In mice, the EAT-2 association with CS1 has an inhibitory effect on the activation of NK cells.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant fragment of human SLAMF7 protein (around aa 249-335) (exact sequence is proprietary)
- 亚型
- IgG1
- Top Product
- Discover our top product SLAMF7 Primary Antibody
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anti-SLAM Family Member 7 (SLAMF7) (AA 23-226) antibody
SLAMF7 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 5G5A4 unconjugated
anti-SLAM Family Member 7 (SLAMF7) antibodySLAMF7 适用: 人, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-SLAM Family Member 7 (SLAMF7) (AA 51-160) antibodySLAMF7 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-SLAM Family Member 7 (SLAMF7) (AA 23-226) antibodySLAMF7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SLAM Family Member 7 (SLAMF7) antibodySLAMF7 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SLAM Family Member 7 (SLAMF7) (AA 1-296) antibodySLAMF7 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1B9 unconjugated
anti-SLAM Family Member 7 (SLAMF7) (AA 1-296) antibodySLAMF7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SLAM Family Member 7 (SLAMF7) (AA 1-335) antibodySLAMF7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SLAM Family Member 7 (SLAMF7) (AA 23-175) antibodySLAMF7 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human tonsil tissue.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- SLAMF7 (SLAM Family Member 7 (SLAMF7))
- 别名
- SLAMF7 (SLAMF7 产品)
- 别名
- RGD1560190 antibody, SLAMF7 antibody, slaf7 antibody, 19A antibody, CD319 antibody, CRACC antibody, CS1 antibody, 19A24 antibody, 4930560D03Rik antibody, SLAM family member 7 antibody, Slamf7 antibody, SLAMF7 antibody, slaf7 antibody
- 背景
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19A, 19A24 protein, CD2 like receptor activating cytotoxic cells, CD2 subset 1, CRACC, CS1, Membrane protein FOAP 12, Novel LY9 (lymphocyte antigen 9) like protein, Protein 19A, SLAM family member 7,SLAMF7 / CS1 / CD319
Cellular localisation: Cell surface - 分子量
- 37kDa
- 基因ID
- 57823, 517265
- UniProt
- Q9NQ25
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