Resistin 抗体 (AA 19-108)
Quick Overview for Resistin 抗体 (AA 19-108) (ABIN7126844)
抗原
See all Resistin (RETN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 19-108
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特异性
- The cysteine-rich, adipose tissue-specific, secretory factor resistin (resistance to Insulin) also known as ADSF, is a secreted hormone that potentially links obesity to diabetes. Resistin is rich in serine and cysteine residues and contains a unique cysteine repeat motif. Resistin and the resistin-like molecules share the characteristic cysteine composition and other signature features. Resistin-like i± is a secreted protein that has restricted tissue distribution and is most highly expressed in adipose tissue. Another family member, resistinlike i², is a secreted protein expressed only in the gastrointestinal tract, particularly in the colon, in both mouse and human. Resistin-like i² expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment of human RETN protein (around aa 19-108) (exact sequence is proprietary)
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亚型
- IgG2b
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human bone marrow or spleen.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Resistin (RETN)
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别名
- RETN
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背景
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Adipose tissue specific secretory factor, ADSF, C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 1, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3, dri, FIZZ3, Found in inflammatory zone 3, HXCP1, Resistin delta2, RETN1, RSTN, XCP1,Resistin (RETN)
Cellular localisation: Secreted -
分子量
- 13kDa
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基因ID
- 56729, 283091
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UniProt
- Q9HD89
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途径
- Feeding Behaviour, Smooth Muscle Cell Migration
抗原
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