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FERMT1 抗体 (AA 216-677)

FERMT1 适用: 人 WB, IP, IHC (f) 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7126830
发货至: 中国
  • 抗原 See all FERMT1 抗体
    FERMT1 (Fermitin Family Member 1 (FERMT1))
    抗原表位
    • 15
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 216-677
    适用
    • 42
    • 22
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 36
    • 6
    小鼠
    克隆类型
    • 38
    • 4
    单克隆
    标记
    • 19
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FERMT1 antibody is un-conjugated
    应用范围
    • 21
    • 15
    • 13
    • 13
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Kindlin-1 (also known as KIND1, KINDLERIN, UNC112-RELATED PROTEIN 1 (URP1) is an important component of cell-extracellular matrix adhesion. Kindlin-1 is involved in cell adhesion, possibly via its interaction with integrins and may mediate TGF-beta 1 signaling during tumor progression. Kindlin-1 has been shown to be significantly upregulated in lung and colon carcinomas. Mutations in the kindlin-1 gene, FERMT1, causes Kindler syndrome. Kindler syndrome is an autosomal recessive disorder characterized by neonatal blistering, sun sensitivity, atrophy, abnormal pigmentation and fragility of the skin. We have developed monoclonal anti-kidlin-1 antibodies. This monoclonal antibody recognizes kindlin-1 in multiple assays including Western blotting, immunoprecipitation, immunohistochemical and immunofluorescent staining.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant protein containing Kindlin-1 (residues 216-677)
    亚型
    IgG2a
    Top Product
    Discover our top product FERMT1 Primary Antibody
  • 应用备注

    Known_Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: 293T whole cell lysate. Human tonsil or liver.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    FERMT1 (Fermitin Family Member 1 (FERMT1))
    别名
    FERMT1 (FERMT1 产品)
    别名
    C20orf42 antibody, DTGCU2 antibody, KIND1 antibody, UNC112A antibody, URP1 antibody, 5830467P10Rik antibody, Kindlin-1 antibody, RGD1306816 antibody, si:ch73-22c10.1 antibody, wu:fc32b07 antibody, fermitin family member 1 antibody, fermitin family member 1 S homeolog antibody, fermitin family homolog 1 antibody, FERMT1 antibody, Fermt1 antibody, fermt1.S antibody, fermt1 antibody, LOC100548276 antibody
    背景
    Fermitin family homolog 1 (Fermt1), Kindlin-1 (KIND1), Kindlerin, Unc-112, UNC112A, URP1, DTGCU2,Kindlin-1 / KIND1
    Cellular localisation: Cytoplasm.
    分子量
    77kDa
    基因ID
    55612, 472054
    UniProt
    Q9BQL6
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