FERMT1 抗体 (AA 216-677)
Quick Overview for FERMT1 抗体 (AA 216-677) (ABIN7126830)
抗原
See all FERMT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 216-677
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特异性
- Kindlin-1 (also known as KIND1, KINDLERIN, UNC112-RELATED PROTEIN 1 (URP1) is an important component of cell-extracellular matrix adhesion. Kindlin-1 is involved in cell adhesion, possibly via its interaction with integrins and may mediate TGF-beta 1 signaling during tumor progression. Kindlin-1 has been shown to be significantly upregulated in lung and colon carcinomas. Mutations in the kindlin-1 gene, FERMT1, causes Kindler syndrome. Kindler syndrome is an autosomal recessive disorder characterized by neonatal blistering, sun sensitivity, atrophy, abnormal pigmentation and fragility of the skin. We have developed monoclonal anti-kidlin-1 antibodies. This monoclonal antibody recognizes kindlin-1 in multiple assays including Western blotting, immunoprecipitation, immunohistochemical and immunofluorescent staining.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant protein containing Kindlin-1 (residues 216-677)
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亚型
- IgG2a
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anti-Fermitin Family Member 1 (FERMT1) (AA 321-420) antibody
FERMT1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fermitin Family Member 1 (FERMT1) (AA 268-297) antibodyFERMT1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fermitin Family Member 1 (FERMT1) (AA 1-677) antibodyFERMT1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Fermitin Family Member 1 (FERMT1) (AA 180-269) antibodyFERMT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D11 unconjugated
anti-Fermitin Family Member 1 (FERMT1) (AA 1-677) antibodyFERMT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fermitin Family Member 1 (FERMT1) (N-Term) antibodyFERMT1 适用: 人, 大鼠, Cow, 犬, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Fermitin Family Member 1 (FERMT1) (AA 268-297) antibodyFERMT1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB23411 unconjugated
anti-Fermitin Family Member 1 (FERMT1) (AA 268-297) antibodyFERMT1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: 293T whole cell lysate. Human tonsil or liver.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- FERMT1 (Fermitin Family Member 1 (FERMT1))
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别名
- FERMT1
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背景
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Fermitin family homolog 1 (Fermt1), Kindlin-1 (KIND1), Kindlerin, Unc-112, UNC112A, URP1, DTGCU2,Kindlin-1 / KIND1
Cellular localisation: Cytoplasm. -
分子量
- 77kDa
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基因ID
- 55612, 472054
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UniProt
- Q9BQL6
抗原
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