ITLN1/Omentin 抗体 (AA 16-141)
Quick Overview for ITLN1/Omentin 抗体 (AA 16-141) (ABIN7126826)
抗原
See all ITLN1/Omentin (ITLN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 16-141
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特异性
- Human intelectin-1 (ITLN-1) is a novel identified galactose binding lectin that is usually expressed in the heart, small intestine, and colon. In normal tissues, human intelectin-1 was mainly secreted from gastrointestinal goblet cells along with mucus into the intestinal lumen, and it was also expressed, to a lesser extent, in mesothelial cells and urinary epithelial cells. It is overexpressed in human malignant pleural mesothelioma (MPM). In contrast, sarcomatoid-type MPMs, biphasic MPMs, and poorly differentiated MPMs are rarely positive for intelectin-1, and it is not expressed in other cancers, except in mucus-producing adenocarcinoma.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (around aa16-141) of human Intelectin-1 (ITLN1) protein (exact sequence is proprietary)
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亚型
- IgG1
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human mesothelioma or colon tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))
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别名
- ITLN1
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背景
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Endothelial lectin HL-1, Galactofuranose binding lectin, hIntL, Intestinal lactoferrin receptor, INTL, ITLN, LFR,Intelectin 1 / Omentin (Epithelioid-Type Malignant Mesothelioma Marker)
Cellular localisation: Cell membrane. Secreted. -
分子量
- 35kDa
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基因ID
- 55600, 50813
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UniProt
- Q8WWA0
抗原
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