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PRMT7 抗体

This anti-PRMT7 antibody is a 小鼠 单克隆 antibody detecting PRMT7 in WB, IF, IP 和 FACS. Suitable for 人.
产品编号 ABIN7126811
发货至: 中国

Quick Overview for PRMT7 抗体 (ABIN7126811)

抗原

See all PRMT7 抗体
PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PRMT7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)
  • 特异性

    Arginine methylation is an irreversible protein modification catalyzed by Arginine methyltransferases, such as PRMT7, which uses S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport and RNA splicing. PRMT7 has two methyltransferase domains, each containing a putative AdoMet-binding motif. The N-terminal methyltransferase domain closely resembles the catalytic core of PRMT5, and the C-terminal domain is most similar to that of PRMT1. Three PRMT7 splice variants have been identified by database analysis. PRMT7 is localized to the nucleus and cytoplasm and moderate expression is observed in adult brain and lung tissues.

    交叉反应 (详细)

    Human. Predicted to react with Rat.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant full-length human PRMT7 protein

    亚型

    IgG1
  • 应用备注

    Known_Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), Western Blot (1-2 μg/mL),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa, MCF7 or HepG2 cells.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

    别名

    PRMT7

    背景

    [Myelin basic protein]-arginine N-methyltransferase PRMT7, Histone-arginine N-methyltransferase PRMT7, KIAA1933, Protein arginine methyltransferase 7, Protein arginine N-methyltransferase 7,PRMT7
    Cellular localisation: Nucleus. Nucleoplasm. Cytoplasm.

    分子量

    78.46kDa

    基因ID

    54496, 640229

    UniProt

    Q9NVM4

    途径

    Ribonucleoprotein Complex Subunit Organization
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