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PLP1 抗体 (AA 272-277)

The 小鼠 单克隆 anti-PLP1 antibody is suitable to detect PLP1 in samples from 人. It has been validated for IHC (f).
产品编号 ABIN7126797
发货至: 中国
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Quick Overview for PLP1 抗体 (AA 272-277) (ABIN7126797)

抗原

See all PLP1 抗体
PLP1 (Proteolipid Protein 1 (PLP1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PLP1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 抗原表位

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    AA 272-277

    特异性

    Proteolipid protein (PLP) is the major myelin protein of the CNS and plays an important role in the formation and maintenance of myelin. PLP may play a role in the compaction and stabilization of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in PLP gene can lead to dysmyelinating diseases. Clone PLP1/4259 is used in the detection of PLP by various analysis methods.

    交叉反应 (详细)

    Human, Mouse, Rat, Tenerife Lizard and Cow.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Synthetic peptide GRGTKF that recognizes the C terminal region (aa272-277) of myelin proteolipid protein.

    亚型

    IgG2a
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human brain tissue.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    PLP1 (Proteolipid Protein 1 (PLP1))

    别名

    PLP1

    背景

    Myelin proteolipid protein, PLP, Lipophilin, PLP1, HLD1, SPG2, PMD, Major myelin proteolipid protein (MMPL), DM20,Proteolipid Protein / Myelin PLP
    Cellular localisation: Membrane

    分子量

    23-25kDa

    基因ID

    5354, 1787

    UniProt

    P60201
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