PLP1 抗体 (AA 272-277)
Quick Overview for PLP1 抗体 (AA 272-277) (ABIN7126797)
抗原
See all PLP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 272-277
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特异性
- Proteolipid protein (PLP) is the major myelin protein of the CNS and plays an important role in the formation and maintenance of myelin. PLP may play a role in the compaction and stabilization of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in PLP gene can lead to dysmyelinating diseases. Clone PLP1/4259 is used in the detection of PLP by various analysis methods.
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交叉反应 (详细)
- Human, Mouse, Rat, Tenerife Lizard and Cow.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Synthetic peptide GRGTKF that recognizes the C terminal region (aa272-277) of myelin proteolipid protein.
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亚型
- IgG2a
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human brain tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- PLP1 (Proteolipid Protein 1 (PLP1))
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别名
- PLP1
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背景
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Myelin proteolipid protein, PLP, Lipophilin, PLP1, HLD1, SPG2, PMD, Major myelin proteolipid protein (MMPL), DM20,Proteolipid Protein / Myelin PLP
Cellular localisation: Membrane -
分子量
- 23-25kDa
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基因ID
- 5354, 1787
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UniProt
- P60201
抗原
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