PIK3R2 抗体 (AA 520-720)
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Quick Overview for PIK3R2 抗体 (AA 520-720) (ABIN7126793)
抗原
See all PIK3R2 (PI3K p85b) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 520-720
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原理
- PIK3R2 / Phosphoinositide-3-kinase regulatory subunit 2 Antibody
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特异性
- Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85°™ and p85 æ), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110°™ and p110 æ interact with p85°™, and p110°™ has also been shown to interact with p85 æ in vitro. p110 79oΩL expression is restricted to white blood cells. It has been shown to bind p85°™ and p85 æ, but it apparently does not phosphorylate these subunits. p110 79oΩL seems to have the capacity to autophosphorylate. p110Á does not interact with the p85 subunits. It has been shown to be activated by °™ and æÁ heterotrimeric G proteins.
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交叉反应 （详细）
- Human.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment of human PIK3R2 protein (around aa 520-720) (exact sequence is proprietary)
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亚型
- IgG2b, kappa
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anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibody
PI3K p85b 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 1-60) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 75-125), (Regulatory Subunit) antibodyPI3K p85b 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠, Cow, 犬 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (Thr232) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (Subunit beta) antibodyPI3K p85b 适用: 人, Cow, 猴 WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal T15 unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5210 unconjugated Recombinant Antibody
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 430-470) antibodyPI3K p85b 适用: 人 WB 宿主: 兔 Polyclonal RB48985 unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human spleen or bladder.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))
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别名
- PIK3R2
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背景
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p85 beta, P85B, Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 2 (p85 beta), Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, Phosphoinositide 3 kinase regulatory subunit polypeptide 2 (p85 beta), PI3 kinase p85 beta subunit, PI3K regulatory subunit beta, PIK3R2, PtdIns-3-kinase regulatory subunit p85-beta
Human spleen or bladder.
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分子量
- 85kDa
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基因ID
- 5296, 371344
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UniProt
- O00459
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途径
- VEGF Signaling, BCR Signaling
抗原
-
