PIK3R2 抗体 (AA 520-720)
Quick Overview for PIK3R2 抗体 (AA 520-720) (ABIN7126793)
抗原
See all PIK3R2 (PI3K p85b) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 520-720
-
特异性
- Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85i± and p85i²), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110i± and p110i² interact with p85i±, and p110i± has also been shown to interact with p85i² in vitro. p110 L expression is restricted to white blood cells. It has been shown to bind p85i± and p85i², but it apparently does not phosphorylate these subunits. p110 L seems to have the capacity to autophosphorylate. p110i³ does not interact with the p85 subunits. It has been shown to be activated by i± and i²i³ heterotrimeric G proteins.
-
交叉反应 （详细）
- Human.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant fragment of human PIK3R2 protein (around aa 520-720) (exact sequence is proprietary)
-
亚型
- IgG2b
-
-
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 1-60) antibody
PI3K p85b 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 75-125), (Regulatory Subunit beta) antibodyPI3K p85b 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠, Cow, 犬 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (Subunit beta) antibodyPI3K p85b 适用: 人, Cow, 猴 WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal T15 unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (Thr232) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 430-470) antibodyPI3K p85b 适用: 人 WB 宿主: 兔 Polyclonal RB48985 unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (Tyr467) antibodyPI3K p85b 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 447-461), (Middle Region) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 445-474) antibodyPI3K p85b 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB13091 unconjugated
-
-
应用备注
-
Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human spleen or bladder.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))
-
别名
- PIK3R2
-
背景
-
P85 beta, P85B, Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 2 (p85 beta), Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, Phosphoinositide 3 kinase regulatory subunit polypeptide 2 (p85 beta), PI3 kinase p85 beta subunit, PI3K regulatory subunit beta, PIK3R2, PtdIns-3-kinase regulatory subunit p85-beta,PIK3R2 / Phosphoinositide-3-kinase regulatory subunit 2
Cellular localisation: Cytoplasm > golgi apparatus. Nucleus. -
分子量
- 85kDa
-
基因ID
- 5296, 371344
-
UniProt
- O00459
-
途径
- VEGF Signaling, BCR Signaling
抗原
-
