PIK3R2 抗体 (AA 520-720)
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Quick Overview for PIK3R2 抗体 (AA 520-720) (ABIN7126793)
抗原
See all PIK3R2 (PI3K p85b) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 520-720
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特异性
- Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85i± and p85i²), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110i± and p110i² interact with p85i±, and p110i± has also been shown to interact with p85i² in vitro. p110 L expression is restricted to white blood cells. It has been shown to bind p85i± and p85i², but it apparently does not phosphorylate these subunits. p110 L seems to have the capacity to autophosphorylate. p110i³ does not interact with the p85 subunits. It has been shown to be activated by i± and i²i³ heterotrimeric G proteins.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment of human PIK3R2 protein (around aa 520-720) (exact sequence is proprietary)
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亚型
- IgG2b
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anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibody
PI3K p85b 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 1-60) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 75-125), (Regulatory Subunit) antibodyPI3K p85b 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠, Cow, 犬 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (Subunit beta) antibodyPI3K p85b 适用: 人, Cow, 猴 WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal T15 unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (Thr232) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 430-470) antibodyPI3K p85b 适用: 人 WB 宿主: 兔 Polyclonal RB48985 unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5210 unconjugated Recombinant Antibody
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human spleen or bladder.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))
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别名
- PIK3R2
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背景
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P85 beta, P85B, Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 2 (p85 beta), Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, Phosphoinositide 3 kinase regulatory subunit polypeptide 2 (p85 beta), PI3 kinase p85 beta subunit, PI3K regulatory subunit beta, PIK3R2, PtdIns-3-kinase regulatory subunit p85-beta,PIK3R2 / Phosphoinositide-3-kinase regulatory subunit 2
Cellular localisation: Cytoplasm > golgi apparatus. Nucleus. -
分子量
- 85kDa
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基因ID
- 5296, 371344
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UniProt
- O00459
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途径
- VEGF Signaling, BCR Signaling
抗原
-
