Phosphoglucomutase 5 抗体
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Quick Overview for Phosphoglucomutase 5 抗体 (ABIN7126784)
抗原
See all Phosphoglucomutase 5 (PGM5) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4 % of the human genome.
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交叉反应 （详细）
- Human, Cow, Mouse, Rat and Rabbit. Predicted to react with Porcine, Avian, and Frog.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Cytoskeletal fraction of the human myometrium tissue extract
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亚型
- IgG2a
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anti-Phosphoglucomutase 5 (PGM5) (AA 1-506) antibody
PGM5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphoglucomutase 5 (PGM5) (N-Term) antibodyPGM5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphoglucomutase 5 (PGM5) (AA 182-296) antibodyPGM5 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: ELISA (For coating, order antibody without BSA), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Human heart muscle or smooth muscle (IHC). Mouse heart tissue lysate (WB).
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Phosphoglucomutase 5 (PGM5)
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别名
- PGM5
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背景
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Aciculin, PGM-RP, PGM5, PGMRP, phosphoglucomutase 5, Phosphoglucomutase-like protein 5, Phosphoglucomutase-related protein,Aciculin / Phosphoglucomutase 5 (PGM5)
Cellular localisation: Cytoplasm -
分子量
- 56kDa
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基因ID
- 5239, 307835
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UniProt
- Q15124
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途径
- Cellular Glucan Metabolic Process
抗原
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