PBX1 抗体
Quick Overview for PBX1 抗体 (ABIN7126761)
抗原
See all PBX1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1,19)(q23,p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92 % and 94 % respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.
-
交叉反应 （详细）
- Human.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant full-length human PBX1 protein
-
亚型
- IgG2b
-
-
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (AA 213-321) antibody
PBX1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4A2 unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (AA 315-430) antibodyPBX1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (Internal Region) antibodyVerified PBX1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (AA 213-321) antibodyPBX1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (AA 311-403) antibodyPBX1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D6 unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (N-Term) antibodyPBX1 适用: 人, 小鼠, 大鼠, Cow, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (AA 311-430) antibodyPBX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (Center) antibodyPBX1 适用: 人 IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (N-Term) antibodyPBX1 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa cells. Expressed in all tissues except in cells of the B and T lineage.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
-
别名
- PBX1
-
背景
-
DKFZp686B09108, Homeobox protein PBX 1, Homeobox protein PBX1, Homeobox protein PRL, Pbx1, Pre B cell leukemia homeobox 1, Pre B cell leukemia transcription factor 1, Pre-B-cell leukemia transcription factor 1, PRL,PBX1 / PRL (Transcription Factor)
Cellular localisation: Nucleus. -
分子量
- 86.1kDa
-
基因ID
- 5087, 557097
-
UniProt
- P40424
抗原
-
