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Recombinant PAX7 抗体 (AA 301-505)

This 兔 单克隆 antibody specifically detects PAX7 in IHC (f). It exhibits reactivity toward 人.
产品编号 ABIN7126760
发货至: 中国
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Quick Overview for Recombinant PAX7 抗体 (AA 301-505) (ABIN7126760)

抗原

See all PAX7 抗体
PAX7 (Paired Box 7 (PAX7))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This PAX7 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 抗原表位

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    AA 301-505

    特异性

    The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant fragment (aa301-505) of human PAX7 protein (exact sequence is proprietary)

    亚型

    IgG
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human rhabdomyosarcoma (RMS) or testicular carcinoma.,

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    PAX7 (Paired Box 7 (PAX7))

    别名

    PAX7

    背景

    HUP1, Paired box gene 7, Paired box homeotic gene 7, Paired domain gene HuP1, PAX7 transcriptional factor, PAX7/FKHR fusion gene, PAX7B, RMS2,PAX7 (Rhabdomyosarcoma Marker)
    Cellular localisation: Nucleus.

    分子量

    57kDa

    基因ID

    5081, 113253

    UniProt

    P23759
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