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Recombinant MYH11 抗体 (AA 1-100)

This anti-MYH11 antibody is a 兔 单克隆 antibody detecting MYH11 in IHC (f). Suitable for 人.
产品编号 ABIN7126733
发货至: 中国

Quick Overview for Recombinant MYH11 抗体 (AA 1-100) (ABIN7126733)

抗原

See all MYH11 抗体
MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This MYH11 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 抗原表位

    • 5
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    AA 1-100

    特异性

    Smooth Muscle Myosin, heavy chain (SMM-HC) is a cytoplasmic structural protein that is a major component of the contractile apparatus of the smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early and is specific for smooth muscle development. SM-MHC stains the intact myoepithelial cell (MEC) layers present in benign and in situ malignant breast and bronchioloalveolar lesions and is therefore very helpful in distinguishing between benign and malignant tumors. The antibody reacts with smooth muscle cells and myoepithelial cells, but not with myofibroblasts. It is very helpful in distinguishing between benign sclerosing breast lesions and infiltrating carcinomas in difficult cases since it strongly stains the myoepithelial layer in the benign lesions while it is negative in the infiltrating carcinomas.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant human fragment corresponding to Myosin residues within aa1-100 of Myosin (Smooth Muscle)

    亚型

    IgG
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human smooth muscle, uterus or breast.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

    别名

    MYH11

    背景

    AAT4, Myosin heavy chain 11 (MYH11), Myosin heavy chain 11 smooth muscle, Smooth muscle myosin heavy chain 11, Myosin-11, SM1, SM2, SMHC, SMMHC,Smooth MuscleMyosin Heavy Chain (SM-MHC) (Leiomyosarcoma & Myoepithelial Cell Marker)
    Cellular localisation: Cytoplasm.

    分子量

    227kDa

    基因ID

    4629, 460109

    UniProt

    P35749
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