MXI1 抗体
Quick Overview for MXI1 抗体 (ABIN7126729)
抗原
See all MXI1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- It is now well established that Myc regulation of cell proliferation and differentiation involves a family of related transcription factors. One such factor, Max, is an obligate heterodimeric partner for Myc and can also form heterodimers with at least four related proteins designated Mad 1, Mxi1 (also designated Mad 2), Mad 3 and Mad 4. Like Mad 1 and Mxi1, association of Mad 3 and Mad 4 with Max results in transcriptional repression. Both Myc and the Mad proteins have short half-lives and their synthesis is tightly regulated, while Max expression is constitutive and relatively stable. Two related mammalian cDNAs have been identified and shown to encode Mad- binding proteins. Both possess sequence homology with the yeast transcription repressor Sin3 including four conserved paired amphipathic helix (PAH) domains. mSin3A and mSin3B specifically interact with the Mad proteins via their second paired amphipathic helix domain (PAH2). It has been suggested that Mad-Max heterodimers repress transcription by tethering mSin3 to DNA as corepressors.
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交叉反应 （详细）
- Human
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human MXI1 protein
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亚型
- IgG2b
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anti-MAX Interactor 1 (MXI1) (AA 1-182) antibody
MXI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B10 unconjugated
anti-MAX Interactor 1 (MXI1) (Middle Region) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 73-182) antibodyMXI1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-MAX Interactor 1 (MXI1) (N-Term) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 75-173) antibodyMXI1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (N-Term) antibodyMXI1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 176-225) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Pig, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 215-264) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Pig, Bat, Hamster, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 170-295) antibodyMXI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 76-295) antibodyMXI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or K562 cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- MXI1 (MAX Interactor 1 (MXI1))
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别名
- MXI1
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背景
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BHLHc11, Class C basic helix-loop-helix protein 11, MAX dimerization protein 2 (MAD2), MAX interacting protein 1, Max interactor 1, Max related transcription factor, MXD2, MXI, MXI1 protein,MXI1
Cellular localisation: Nucleus. -
分子量
- 26/22/33/21 kDa (isoforms)
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基因ID
- 4601
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UniProt
- P50539
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途径
- Maintenance of Protein Location
抗原
-
