FOXB2 抗体 (AA 1-200)
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北京 101111
Quick Overview for FOXB2 抗体 (AA 1-200) (ABIN7126716)
抗原
See all FOXB2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- FOXB2 (Transcription Factor) Antibody
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特异性
- The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.
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交叉反应 (详细)
- Human. Predicted to react in Mouse and Rat.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa1-200) of human FOXB2 protein (exact sequence is proprietary)
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亚型
- IgG2a
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应用备注
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Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or HepG2 cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- FOXB2 (Forkhead Box B2 (FOXB2))
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别名
- FOXB2
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背景
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bA159H20.4, Forkhead box B2, Forkhead box protein B2, FOXB 2, Foxb2
HeLa or HepG2 cells.
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分子量
- 45.58kDa
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基因ID
- 442425, 553843
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UniProt
- Q5VYV0
抗原
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