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SMAD9 抗体

This anti-SMAD9 antibody is a 小鼠 单克隆 antibody detecting SMAD9 in IF 和 FACS. Suitable for 人.
产品编号 ABIN7126668
发货至: 中国

Quick Overview for SMAD9 抗体 (ABIN7126668)

抗原

See all SMAD9 抗体
SMAD9 (SMAD Family Member 9 (SMAD9))

适用

  • 64
  • 38
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宿主

  • 59
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  • 1
小鼠

克隆类型

  • 64
  • 2
单克隆

标记

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This SMAD9 antibody is un-conjugated

应用范围

  • 40
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Immunofluorescence (IF), Flow Cytometry (FACS)
  • 特异性

    Smad proteins, the mammalian homologs of the Drosophila mothers against dpp (Mad) have been implicated as downstream effectors of TGFi²/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MadH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFi² and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFi² signaling by interfering with TGFi²-mediated phosphorylation of other Smad family members.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant full-length human SMAD9 protein

    亚型

    IgG1
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa, U87 or Ramos cells.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    SMAD9 (SMAD Family Member 9 (SMAD9))

    别名

    SMAD9

    背景

    MAD homolog 9, Madh6, Mothers against decapentaplegic homolog 9, Mothers against DPP homolog 9, SMAD family member 9, SMAD, mothers against DPP homolog 9 (Drosophila), SMAD8A, SMAD8B, Smad9,SMAD9
    Cellular localisation: Cytoplasm. Nucleus. In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4.

    分子量

    52.4kDa

    基因ID

    4093, 123119

    UniProt

    O15198
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