Lactoferrin 抗体 (AA 614-645)
Quick Overview for Lactoferrin 抗体 (AA 614-645) (ABIN7126647)
抗原
See all Lactoferrin (LTF) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 614-645
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特异性
- Ferritin and transferrins manage necessary iron-binding functions for iron metabolism. Transferrins comprise a class of single-chain, two-sited, metal-binding proteins expressed throughout the fluid and cells of vertebrates. The three major types of transferrin include serotransferrin, lactotransferrin (lactoferrin) and ovotransferrin. Lactoferrin is found in milk, tears and leukocytes. It degrades an IgA1protease secreted by Haemophilus influenzae and, consequently, allows the human IgA1antibody to effectively abolish Haemophilus influenzae colonization. Lactoferrin also attenuates the pathogenic potential of Haemophilus influenzae by proteolytic degradation of the Hap adhesin. While lactoferrin may aid in the transmission of human T cell leukemiavirus type 1, it inhibits HIV-1 replication at the level of viral fusion and entry into cells. The inhibitory effects of lactoferrin on mixed lymphocyte reactions suggest that it may have the ability to sense the activation status of lymphocytes.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (around aa614-645) of human Lactotransferrin protein (exact sequence is proprietary)
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亚型
- IgG2b
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anti-Lactotransferrin (LTF) antibody
LTF 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) (AA 25-352) antibodyLTF 适用: 山羊 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) antibodyLTF 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB22673 unconjugated
anti-Lactotransferrin (LTF) (AA 219-248) antibodyLTF 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB11921 unconjugated
anti-Lactotransferrin (LTF) (AA 500-710) antibodyLTF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) (AA 63-193) antibodyLTF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) (AA 28-351) antibodyLTF 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) antibodyLTF 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) (AA 25-352) antibodyLTF 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) (Internal Region) antibodyVerified LTF 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human lactating breast or prostate tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Lactoferrin (LTF) (Lactotransferrin (LTF))
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别名
- LTF
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背景
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GIG12, Growth inhibiting protein 12, HLF2, Kaliocin 1, Lactoferrin, Lactoferroxin-C, Lactotransferrin, LF, LTF, Neutrophil lactoferrin, Talalactoferrin,Lactotransferrin / Lactoferrin / LTF
Cellular localisation: Secreted. -
分子量
- 78kDa
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基因ID
- 4057, 529517
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UniProt
- P02788
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途径
- Transition Metal Ion Homeostasis
抗原
-
