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ITGB1 抗体

This anti-ITGB1 antibody is a 小鼠 单克隆 antibody detecting ITGB1 in ELISA, IHC (f) 和 Coat. Suitable for 人.
产品编号 ABIN7126605
发货至: 中国

Quick Overview for ITGB1 抗体 (ABIN7126605)

抗原

See all ITGB1 抗体
ITGB1 (Integrin beta 1 (ITGB1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ITGB1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Coating (Coat)
  • 特异性

    Recognizes CD29. Binds to the cell membrane of T- and B- lymphocytes, monocytes, platelets, fibroblasts, endothelial cells, mast cells and smooth muscle cells. CD29 is an adhesion receptor and co-stimulatory molecule. This antigen was initially characterized as GPIIa on platelets and as the common b1 subunit of the very late antigen (VLA) protein family. CD29 forms a non-covalent heterodimeric complex with integrin alpha subunits. It also mediates adhesion to invasion and thrombospondin.

    交叉反应 (详细)

    Human. Does not react with Mouse or Rat.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Purified human beta 1 integrin from HT1080 fibrosarcoma cell extract.

    亚型

    IgG1
  • 应用备注

    Known_Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: HT1080 whole cell lysate. HeLa cell line.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    ITGB1 (Integrin beta 1 (ITGB1))

    别名

    ITGB1

    背景

    Fibrinogen Receptor beta subunit, FNRB, Glycoprotein IIa (GPIIA), Integrin beta-1 (ITGB1), integrin VLA-4 beta subunit, MDF2, MSK12, Very Late Activation Protein beta Polypeptide, VLA-4 subunit beta, VLA-BETA, VLAB,CD29 (Stem Cell Marker)
    Cellular localisation: Cell Surface

    分子量

    110kDa (non-reduced) & 130kDa (reduced)

    基因ID

    3688, 643813

    UniProt

    P05556

    途径

    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
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