Inhibin alpha 抗体 (AA 233-264)
Quick Overview for Inhibin alpha 抗体 (AA 233-264) (ABIN7126592)
抗原
See all Inhibin alpha (INHA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 233-264
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特异性
- It recognizes a 47 kDa protein, which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same i± subunit, covalently linked to 1 of 2 distinct subunits, i²-i± or i²-i². Originally isolated from ovarian follicular fluid and characterized as a disulphide-linked dimeric glycoprotein, inhibin belongs to the transforming growth factor i² (TFGi²) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity. Inhibin antibody is also used to make the differential diagnosis of intra-uterine vs. ectopic pregnancy in endometrial curetting.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- A synthetic peptide corresponding to Human Inhibin alpha aa 233-264. Note that this peptide corresponds to the N-terminus of the mature region of the human inhibin alpha subunit.
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亚型
- IgG2a
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anti-Inhibin, alpha (INHA) (AA 301-366) antibody
INHA 适用: 大鼠, 小鼠, Pig WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Inhibin, alpha (INHA) (AA 25-363) antibodyINHA 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Inhibin, alpha (INHA) (AA 233-362) antibodyINHA 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-561R unconjugated Recombinant Antibody
anti-Inhibin, alpha (INHA) (AA 19-366) antibodyINHA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inhibin, alpha (INHA) antibodyINHA 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 4E2 unconjugated
anti-Inhibin, alpha (INHA) (AA 79-108), (N-Term) antibodyINHA 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB18802 unconjugated
anti-Inhibin, alpha (INHA) (AA 281-366) antibodyINHA 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Inhibin, alpha (INHA) (AA 233-366) antibodyINHA 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Inhibin, alpha (INHA) (AA 240-366) antibodyINHA 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Inhibin, alpha (INHA) (AA 25-363) antibodyINHA 适用: 人 WB 宿主: 小鼠 Monoclonal C1 unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human prostate or testis.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Inhibin alpha (INHA) (Inhibin, alpha (INHA))
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别名
- INHA
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背景
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A inhibin subunit, IHA, inhA, Inhibin alpha chain, Inhibin alpha subunit,Inhibin, alpha (INHA) (Gonadal Cell Marker)
Cellular localisation: Cytoplasmic (secreted) and Nuclear -
分子量
- 47kDa
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基因ID
- 3623, 407506
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UniProt
- P05111
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途径
- Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
抗原
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